T-TEER Cuts Heart Failure Hospitalizations by 40%

The ALERT trial, presented at ACC.26 and published in JACC, shows that automated electronic clinician notification alerts in the electronic health record (EHR) can meaningfully speed up the evaluation and treatment of patients with severe aortic stenosis (AS) or severe mitral regurgitation (MR). 

In this cluster‑randomized study across 35 U.S. hospitals, 765 clinicians and 2,016 echocardiograms were randomized to an Alert or No Alert group.

Using a hierarchical win‑ratio analysis, the alert group showed superior outcomes (win ratio 1.27; p = 0.007), with higher rates of valve intervention (13% vs. 10%) and multidisciplinary heart‑team evaluation (23% vs. 18%), and shorter times to both endpoints. 

The effect was consistent for AS and MR and across subgroups. 

The authors conclude that EHR‑integrated alerts are a practical, scalable way to reduce undertreatment of valvular heart disease and improve timely access to specialized valve‑disease care in routine clinical practice.